Poster: Origin of Normal and Neoplastic B Cells

B-cell diversity is generated in a multistep process in which abnormal B-cell development and function can lead to malignant transformation. Advances in the understanding of the regulatory processes that control B-cell lymphopoiesis and function have enabled proper classification of B-cell neoplasms and the development of targeted therapies. 

Download this poster to get an in-depth understanding of:

• B-cell lymphopoiesis, activation and differentiation
• B-cell malignancies based on a cell-of-origin approach
• Signaling and transcription networks that can be potentially targeted for therapy