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Feature BD ChloraPrep™ Other Antiseptics BD ChloraPrep™ value
Formulation

Proven broad spectrum, rapid acting antiseptic combination of 2% CHG and 70% IPA with the option for tint. The formulation contains no additional excipients.
Available Sizes

Vascular and Surgical sizes for consistency in prepping processes.
Sterile Solution

Less than 1 in a million chance that a viable microorganism can exist in the solution.15
Persistence

At least 7 days.16
Studies & Independent Data

Supported by more than 60 published peer-reviewed clinical studies.
Tint Options

Hi-Lite Orange™, Scrub Teal™, and clear for different skin tones.
Acting in the presence of organic matter

Not neutralized by blood or organic matter.17


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Maintaining low levels of bacteria on the skin while healing is important to minimize bacteria entering the incision site or skin break.1-3


While a mature, intact epidermis is an effective barrier in preventing infection, surgery and other invasive procedures break the skin’s barrier, allowing migration of skin-dwelling and environmental microorganisms into the wound, increasing the risk of local or systemic infection.1-3

Why persistence matters:

  • Surgery and other invasive procedures break the skin’s barrier, allowing skin-dwelling microorganisms to migrate into the wound, increasing risk of infection.1-3
  • Once the skin barrier is broken, the inflammatory phase of wound healing (when microorganisms are killed in the wound by immune cells) peaks at 24-48 hours and lasts for several days. Persistence can help minimize the number of microbes that enter the wound during this time period.4-6
  • Re-epithelization works to reestablish the epithelial barrier and promote wound closure over days to weeks.4-6
  • Many factors can lead to impaired healing of wounds, including bacterial colonization.7
  • Recommended by numerous clinical guidelines.8-14

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Unparalleled flexibility for various patients and procedures

Our extensive family of alcohol based, fully sterile antiseptic products are advancing safety by assuring sterility. We’ve made breakthroughs in antiseptic sterilization, achieving what some manufacturers have asserted as impossible, delivering 1,000 times the required minimum sterility assurance.18

With a selection of sizes, tints, and alcohol based formulations, you can tailor your choice based on surface area, type of site for surgery, patient skin color, and possible sensitivity to CHG. Access to this portfolio can help you standardize your skin preparation practice with the potential for a positive cost impact.

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Learn more about the persistence of BD skin antiseptics and download the Antimicrobial persistence of two alcoholic preoperative skin preparation solutions.

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While a mature, intact epidermis is an effective barrier in preventing infection, surgery and other invasive procedures break the skin’s barrier, allowing migration of skin-dwelling and environmental microorganisms into the wound, increasing the risk of local or systemic infection.1-3

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Proprietary single-use applicators with sterile solution

Standardize your practice with BD ChloraPrep™ Patient Preoperative Skin Preparation with sterile solution and BD PurPrep™ Patient Preoperative Skin Preparation with sterile solution, and trust in full sterility developed with breakthrough science that is raising the bar for antiseptic skin preps.

All-in-one, single-use applicator allows for thorough, aseptic "no touch" technique

Dual formulation of 2% CHG and 70% isopropyl alcohol (IPA)

Dual formulation of PVP-I (0.83% available iodine) and 72.5% IPA

Proprietary tinting process provides enhanced visualization for added assurance

Foam sponge helps control solution flow and enables a gentle scrubbing motion for thorough coverage2

BD ChloraPrep™ Patient Preoperative Skin Preparation with sterile solution

The most persistent chlorhexidine (CHG) based skin antiseptic with sterile solution.


BD PurPrep™ Patient Preoperative Skin Preparation with sterile solution

A sterile, effective alternative when a CHG plus alcohol solution is not ideal.




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Clinically Proven


Persistent


Sterile Solution



BD ChloraPrep™ Patient Preoperative Skin Preparation with Sterile Solution delivers standardized, powerful, persistent antimicrobial protection that is backed by more than 60 published studies and has been trusted by healthcare providers for more than 21 years.

Learn more about the persistence of BD skin antiseptics and download the Antimicrobial persistence of two alcoholic preoperative skin preparation solutions.

REFERENCES

1. Florman S, Nichols RL. Current Approaches for the Prevention of Surgical Site Infections. American Journal of Infectious Diseases. 2007;3(1). 2. Elliott TS, Moss HA, Tebbs SE, et al. Novel approach to investigate a source of microbial contamination of central venous catheters. Eur J Clin Microbiol Infect Dis. 1997;16(3):210-213. 3. Maki DG. Infections Caused by Intravascular Devices Used for Infusion Therapy: Pathogenesis, Prevention, and Management. In: Bisno AL, Waldvogel FA, eds. Infections Associated with Indwelling Medical Devices. 2nd ed.1994. 4. Wilkinson HN, Hardman MJ. Wound healing: cellular mechanisms and pathological outcomes. Open Biol. 2020;10(9):200223. 5. desJardins-Park HE, Mascharak S, Chinta MS, Wan DC, Longaker MT. The Spectrum of Scarring in Craniofacial Wound Repair. Front Physiol. 2019;10:322. 6. Baum CL, Arpey CJ. Normal cutaneous wound healing: clinical correlation with cellular and molecular events. Dermatol Surg. 2005;31(6):674-686; discussion 686. 7. Wallace HA, Basehore BM, Zito PM. Wound Healing Phases. In: StatPearls. Treasure Island (FL): StatPearls Publishing 8. CDC, Berríos-Torres SI, Umscheid CA, et al. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg. 2017;152(8):784-791. 9. WHO. Global Guidelines for the Prevention of Surgical Site Infection, second edition. WHO Guidelines Approved by the Guidelines Review Committee. 2018. 10. Lok CE, Huber TS, Lee T, et al. KDOQI Clinical Practice Guideline for Vascular Access: 2019 Update. American Journal of Kidney Diseases. 2020;75(4):S1-S164. 11. Ling ML, Apisarnthanarak A, Abbas A, et al. APSIC guidelines for the prevention of surgical site infections. Antimicrobial Resistance & Infection Control. 2019;8(1):174. 12. Ling ML, Apisarnthanarak A, Jaggi N, et al. APSIC guide for prevention of Central Line Associated Bloodstream Infections (CLABSI). Antimicrobial Resistance & Infection Control. 2016;5(1):16. 13. NICE. Healthcare-associated infections: prevention and control in primary and community care. In: National Institute for Health and Care Excellence (UK) 14. O'Grady NP, Alexander M, Burns LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2011;52(9):e162-193. 15. Degala, et al. United States Patent 9,078,934. July 14, 2015 16. Beausoleil C, Comstock SL, Werner D, Li L, Eby JM, Zook EC. Antimicrobial persistence of two alcoholic preoperative skin preparation solutions. J Hosp Infect. 2022 Nov;129:8-16 17. Mimoz, O et al. Chlorhexidine compared with povidone-iodine as skin preparation before blood culture. A randomized, controlled trial. Annals of internal medicine vol. 131,11 (1999): 834-7 18. Byron Lambert, Jeffrey Martin, in Biomaterials Science (Third Edition), 2013.

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