Putting more within reach

Enabling subcutaneous delivery of large volume, high viscosity biologics

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In this webinar we have:

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Review our 6 scientific posters

October 22-23, 2019

During conference breajsn hear from our experts who created our posters

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Date
00/00/00/ 11:30am

main subtitle

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aliquam id leo at sapien blandit rhoncus. Interdum et malesuada fames ac ante ipsum primis in faucibus. Quisque ultrices, lorem eu maximus ornare, massa dui porta nunc, sed efficitur nibh lorem at dolor. Sed eget semper lectus.

Lorem Ipsum

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aliquam id leo at sapien blandit rhoncus. Interdum et malesuada fames ac ante ipsum primis in faucibus. Quisque ultrices, lorem eu maximus ornare, massa dui porta nunc, sed efficitur nibh lorem at dolor. Sed eget semper lectus.

Jenny DOE
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Institut of Lorem Ipsum

Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas vestibulum tortor quam.

Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas vestibulum tortor quam.

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Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas vestibulum tortor quam.


Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas vestibulum tortor quam.

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Ibus exped et ape

Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas vestibulum tortor quam.

Ibus exped et ape

Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas vestibulum tortor quam.

Due to its high viscosity, injecting hyaluronic acid puts a lot of pressure on a syringe. That’s why hyaluronic acid manufacturers prioritize needle connection and LLA rotation issues that cause leakage.3 Our BD Hylok Syringe has:

  • A robust LLA design that reduces the risk of rotation1,2, allowing users to tightly screw on the needle.
  • A demonstrated record of excellent performance after terminal steam sterilization over time.1+

Discover more about our BD Hylok™ Syringe and our entire family of injectable delivery systems >

+ terminal steam sterilization at 121°C / 2 cycles / 20min

Due to its high viscosity, injecting hyaluronic acid puts a lot of pressure on a syringe. That’s why hyaluronic acid manufacturers prioritize needle connection and LLA rotation issues that cause leakage.3 Our BD Hylok Syringe has:

  • A robust LLA design that reduces the risk of rotation1,2, allowing users to tightly screw on the needle.
  • A demonstrated record of excellent performance after terminal steam sterilization over time.1+

Discover more about our BD Hylok™ Syringe and our entire family of injectable delivery systems >

+ terminal steam sterilization at 121°C / 2 cycles / 20min

Due to its high viscosity, injecting hyaluronic acid puts a lot of pressure on a syringe. That’s why hyaluronic acid manufacturers prioritize needle connection and LLA rotation issues that cause leakage.3 Our BD Hylok Syringe has:

  • A robust LLA design that reduces the risk of rotation1,2, allowing users to tightly screw on the needle.
  • A demonstrated record of excellent performance after terminal steam sterilization over time.1+

Discover more about our BD Hylok™ Syringe and our entire family of injectable delivery systems >

+ terminal steam sterilization at 121°C / 2 cycles / 20min

360° rotation knob is effectively sized, contoured and located to enable easy instrument rotation.

360° rotation knob is effectively sized

360° rotation knob is effectively sized

360° rotation knob is effectively sized


Engineered for superior performance with hyaluronic acid

Did you know that 72% of decision makers prefer glass syringes over plastic? Explore the benefits of the BD Hylok™ Glass Syringe and other unique features.3

BD Hylok™ Glass Prefillable Syringe for hyaluronic acid

Screw on tip cap
Easy to use and intuitive tip cap with proven user preference2

New bonding technology
Reduced risk of LLA disconnection/rotation1,2

New LLA thread design
Safe and robust needle connection4

Glass barrel
Limited risks and costs associated with potential container change

Testimonials

See how devices like our BD Hylok™ Syringe are changing the way dermatologists look at glass syringe performance



Introducing the BD Libertas™ Wearable Injector with Peel, Stick & Click™ process

Designed for large volume or high viscosity†† fixed dose subcutaneous injection1

  • Patient ready-to-use design* requires no end-user filling or assembly1
  • Enables hands-free§ drug delivery1
  • Features automated needle insertion and retraction1
  • Provides audible, visual or tactile feedback indicators before, during and after injection1
Download product summary


2-5 mL or 5-10 mL.
††up to 50 cP.
*Pharma filled and assembled
§Designed to inject the drug therapy hands-free once activated

Prioritizing safety, convenience and usability throughout the design

Pre-attached adhesive pad

Transparent viewing window for drug and drug delivery visibility

Color-coded status indicator

Push button activation

  • Single use, fixed dose, prefillable design
  • Dose delivery options: 2-5 mL or 5-10 mL
  • Mechanical spring-based power source without battery or heavy metals disposal concerns1,2
  • Integrated BD Neopak™ glass primary container technology

Designed with pharma's operational processes in mind


BD Libertas™ Wearable Injector has five component modules

  • Designed for pharma fill/finish utilizing standardized syringe tubs and commercial prefillable syringe filling equipment and processes1
  • 100% mechanical design that does not require separate software or electronics supplier management and revision controls2

Container and device samples available upon request.

PS_Libertas_5components_sm.png

Delivering the advantage of experience



More than 50 pre-clinical and clinical studies completed

BD has conducted over 50 BD pre-clinical3 and clinical4 studies to inform the design and development of the BD Libertas™ Wearable Injector.



High device acceptance demonstrated

BD reinforced its commitment to innovation by completing a 52-subject human trial for its award-winning* 2-5 mL BD Libertas™ Wearable Injector.5 100% of study subjects responded likely to use if prescribed.5** Results of the human clinical trial with the 2-5 mL BD Libertas™ Wearable Injector are published in Clinical and Translational Science.5



*BD Libertas™ Wearable Injector and DCA Design International have won two design awards: the Good Design® Award and the iF Design Excellence Award.


**Early feasibility clinical study of investigational BD Libertas™ Wearable Injector (WI) evaluated 5 mL, non-Newtonian ~8 cP subcutaneous placebo injections in 52 healthy adult subjects of ≥18.5 kg/m2 BMI divided into 2 age groups (18-64 or ≥65 years) for functionality, tissue effects, subject tolerability and acceptability.


Access the full published journal article “Clinical Evaluation of an Investigational 5 mL Wearable Injector in Healthy Human Subjects” below.

Request article access


Access the full published journal article “Clinical Evaluation of an Investigational 5 mL Wearable Injector in Healthy Human Subjects” below.

Request article access


*BD LibertasTM Wearable Injector and DCA Design International have won two design awards: the Good Design Award and the iF Design Excellence Award.

**Early feasibility clinical study of investigational BD Libertas™ Wearable Injector (WI) evaluated 5 mL, non-Newtonian ~8cP subcutaneous placebo injections in 52 healthy adult subjects of ≥18.5kg/m2 BMI divided into 2 age groups (18-64 or ≥65 years) for functionality, tissue effects, subject tolerability and acceptability.

Learn how BD supports successful commercialization of combination products by enabling the delivery of biologics.

Learn more

Delivering the advantage of experience



More than 50 pre-clinical3 and clinical studies4

BD has conducted over 50 BD pre-clinical3 and clinical4 studies to inform the design and development of the BD Libertas™ Wearable Injector.



High device acceptance

BD reinforced its commitment to innovation by completing a 52-subject human trial for its award-winning 2-5 mL BD LibertasTM Wearable Injector.5 100% of study subjects likely to use if prescribed.5** Results of the human clinical trial with the 2-5 mL BD LibertasTM Wearable Injector are published in Clinical and Translational Science.5

*BD LibertasTM Wearable Injector and DCA Design International have won two design awards: the Good Design Award and the iF Design Excellence Award.

**Early feasibility clinical study of investigational BD Libertas™ Wearable Injector (WI) evaluated 5 mL, non-Newtonian ~8cP subcutaneous placebo injections in 52 healthy adult subjects of ≥18.5kg/m2 BMI divided into 2 age groups (18-64 or ≥65 years) for functionality, tissue effects, subject tolerability and acceptability.


Access the full published journal article “Clinical Evaluation of an Investigational 5 mL Wearable Injector in Healthy Human Subjects” below.


Request article access


Let's have a conversation

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Let's have a conversation

Let's have a conversation

REFERENCES

1. Design Input Specification for BD Libertas™ Platform [Internal report]. Franklin Lakes, USA: Becton, Dickinson and Company; 2014. Revision: 05
2. Design Output Specification for BD Libertas™ Platform [Internal report]. Franklin Lakes, USA: Becton Dickinson and Company; 2017 Revision: 04
3. ADDS Libertas Program Preclinical Study List BDTI Parenteral Sciences COE.
4. ADDS Libertas Program Clinical Study List BDTI Parenteral Sciences COE.
5. Woodley, W. D. et al. Clinical Evaluation of an Investigational 5ml Wearable Injector in Healthy Human Subjects. Clin Transl Sci. 2021 May; 14(3):859-869. doi: 10.1111/cts.12946.

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